Naphazoline hydrochloride

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

Naphazoline HydroHClide 是一种眼部血管收缩剂和咪唑啉衍生物拟交感胺。

Naphazoline hydrochloride is an ocular vasoconstrictor and imidazoline derivative sympathomimetic amine.(In Vivo):Naphazoline hydrochloride (0.2 mg/kg, 10 μl per eye; IP, once) reduces histamine or antigen-induced conjunctival vascular hyperpermeability in mice, and reduces conjunctivitis in mice via effects on inflammation, NGF and VEGF.

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Naphazoline hydrochloride (0.2 mg/kg, 10 μl per eye; IP, once) reduces histamine or antigen-induced conjunctival vascular hyperpermeability in mice, and reduces conjunctivitis in mice via effects on inflammation, NGF and VEGF. Animal Model:Female wild-type BALB/c mice (4-5 weeks, 18 ± 2 g, n=8/group, allergic conjunctivitis mouse model established using histamine or an antigen (ovalbumin))Dosage:0.2 mg/mL, 10 μl per eye Administration:Intraperitoneal injection (IP), once Result:Significantly suppressed conjunctival dye leakage in mice with histamine or antigen?induced conjunctival vascular hyperpermeability. Reduced inflammatory reactions and the levels of IL-1β, IL-6, IFN-γ, and IL-4. Reduced the levels of IgE, GMCSF, NGF and VEGF in antigen-induced conjunctival vascular hyperpermeability mice.

2-(1-Naphthylmethyl)-2-imidazoline

Angiogenesis

Adrenergic Receptor

Adrenergic Receptor

Cardiovascular Disease

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550-99-2

246.74

C14H15ClN2

>98% (HPLC)

Ethanol: 22 mg/mL (89.16 mM); Water: 49 mg/mL (198.58 mM); DMSO: 17 mg/mL (68.89 mM)

[H]Cl.C1(CC2=C3C=CC=CC3=CC=C2)=NCCN1

2-(naphthalen-1-ylmethyl)-4,5-dihydro-1H-imidazole hydrochloride

(-20℃)

With Ice Pack

≥ 2 years